HAPPY NEW YEAR 2011

WHY do we need good health ?

Is there anybody in this world who does not need good health ?

• Everybody needs good health. As the saying goes “health is wealth”
• Like knowledge, health is one of the priceless things in this world we can have IF we decide to have it BUT we need to work for it.

Why do some people take for granted the importance of good health ?

• It is simply because of LACK OF KNOWLEDGE.
• Everybody will die but dying in pain and miserably because of lack of good health is a choice and not a destiny
• If people really know the consequences of lack of good health they will desire to have good health.

Health is something you need throughout your life.

• Can you imagine how your life would look like without having a good health ?
• Can you imagine the lives of your loveones if they do not have good health ?

Health is something you can enjoy 24 hours a day.

• It is something you can bring wherever you go whether you work, spend time with your loveones or even when you go to sleep.
• You may be able to buy the most expensive or luxurious things in the world like cars, jewelries, house, etc.. but can these things be enjoyed 24 hours a day especially during sleeping time ?
• Can these things be brought wherever and whenever a person wishes to bring it?

Good health is one of the things you need to get wealth.

• How can you earn money if you do not go to work because you are sick ?
• How can you do business if you are sick ?
• What will happen to us if our loveones are sick ?
• Is there anybody who wants their income to be spent for hospital expenses ?
• Is there anybody who wants their time to be spent for hospital activities ?

Good health is one of the things you need to spend quality time with your loveones

• How can you spend quality time with your loveones if you are sick or if they are sick ?

Possible consequences of absence of good health.

• Physical pain. Sickness and diseases are usually painful to the body.
• Mental anguish and emotional disturbance. Too much thinking of your and your loveones bad health conditions can cause stress which will worsen health condition.
• Income disturbance / Costly living. You cannot work and you cannot do business even if you want because you are sick or your loveones are sick. You need to pay for hospital bills. Even if you have medical insurance, once your body is opened because of major medical operation you will never have the same life before.
• Knoweldge barrier. You need to stop to study because you are sick. Your children cannot go to school to learn because they are sick hence they will miss lessons from school.
• Burden to others. Instead of being a support / help to your family you become a burden to them hence they suffer. EVERYONE SUFFERS.
• Limited fellowship and lack of social life. Lost of quality time. Your time to fellowship with your loveones and friends are limited by your sick condition.
• Self-pity. You cannot do what you want to do because you are sick. You will usually feel useless.
• Dream killer. You will stop dreaming because your dreams will be overcome by your sick condition.
• Regret. You blame yourself or others for your bad health condition.
• Everybody will die but choosing to die experiencing the above possible consequences of absence of good health IS A CHOICE NOT A DESTINY.
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• Source: Internet 

Eid Greetings

Eid Mubaruk to all DXN  Members and Leaders

Eid & New year promotion of DXN Bangladesh

An Evening with International Leaders

The Other Name of Happiness Called - DXN: International Success Story

The Other Name of Happiness Called - DXN: International Success Story

Monthly Meeting Schedule for October- 2010

Eating fruits - SOME GOOD READING FOR EATING OF FRUITS

Eating Fruit - this opened my eyes.

Dr Stephen Mark treats terminal ill cancer patients by "un-orthodox" way and many patients recovered. He believes on natural healing in the body against illnesses. See the article below.

Dear Shereen,
Thanks for the email on fruits and juices. It is one of the strategies to heal cancer. As of late, my success rate in curing cancer is about 80%. Cancer patients shouldn't die. The cure for cancer is already found. It is whether you believe it or not? I am sorry for the hundreds of cancer patients who die under the conventional treatments.. .

Thanks and God bless. 

Dr Stephen Mark

We all think eating fruits means just buying fruits, cutting it and just popping it into our mouths. It's not as easy as you think. It's important to know how and when to eat.
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What is the correct way of eating fruits? 
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IT MEANS NOT EATING FRUITS AFTER YOUR MEALS! * FRUITS SHOULD BE EATEN ON AN EMPTY STOMACH. 
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If you eat fruit like that, it will play a major role to detoxify your system, supplying you with a great deal of energy for weight loss and other life activities. 
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FRUIT IS THE MOST IMPORTANT FOOD. Let's say you eat two slices of bread and then a slice of fruit. The slice of fruit is ready to go straight through the stomach into the intestines, but it is prevented from doing so. 
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In the meantime the whole meal rots and ferments and turns to acid. The minute the fruit comes into contact with the food in the stomach and digestive juices, the entire mass of food begins to spoil.... 
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So please eat your fruits on an empty stomach or before your meals! You have heard people complaining — every time I eat watermelon I burp, when I eat durian my stomach bloats up, when I eat a banana I feel like running to the toilet, etc — actually all this will not arise if you eat the fruit on an empty stomach. The fruit mixes with the putrefying other food and produces gas and hence you will bloat! 
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Graying hair, balding, nervous outburst, and dark circles under the eyes all these will NOT happen if you take fruits on an empty stomach. 
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There is no such thing as some fruits, like orange and lemon are acidic, because all fruits become alkaline in our body, according to Dr. Herbert Shelton who did research on this matter. If you have mastered the correct way of eating fruits, you have the Secret of beauty, longevity, health, energy, happiness and normal weight. 
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When you need to drink fruit juice - drink only fresh fruit juice, NOT from the cans. Don't even drink juice that has been heated up. Don't eat cooked fruits because you don't get the nutrients at all. You only get to taste. Cooking destroys all the vitamins. 
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But eating a whole fruit is better than drinking the juice. If you should drink the juice, drink it mouthful by mouthful slowly, because you must let it mix with your saliva before swallowing it. You can go on a 3-day fruit fast to cleanse your body. Just eat fruits and drink fruit juice throughout the 3 days and you will be surprised when your friends tell you how radiant you look! 
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KIWI: Tiny but mighty. This is a good source of potassium, magnesium, vitamin E & fiber. Its vitamin C content is twice that of an orange.
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APPLE: An apple a day keeps the doctor away? Although an apple has a low vitamin C content, it has antioxidants & flavonoids which enhances the activity of vitamin C thereby helping to lower the risks of colon cancer, heart attack & stroke.
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STRAWBERRY: Protective Fruit. Strawberries have the highest total antioxidant power among major fruits & protect the body from cancer-causing, blood vessel-clogging free radicals.
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ORANGE : Sweetest medicine. Taking 2-4 oranges a day may help keep colds away, lower cholesterol, prevent & dissolve kidney stones as well as lessens the risk of colon cancer.
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WATERMELON: Coolest thirst quencher. Composed of 92% water, it is also packed with a giant dose of glutathione, which helps boost our immune system. They are also a key source of lycopene — the cancer fighting oxidant. Other nutrients found in watermelon are vitamin C & Potassium. 
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GUAVA & PAPAYA: Top awards for vitamin C. They are the clear winners for their high vitamin C content.. Guava is also rich in fiber, which helps prevent constipation. Papaya is rich in carotene; this is good for your eyes.
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Drinking Cold water after a meal = Cancer! Can u believe this?? For those who like to drink cold water, this article is applicable to you. It is nice to have a cup of cold drink after a meal. However, the cold water will solidify the oily stuff that you have just consumed. It will slow down the digestion... Once this 'sludge' reacts with the acid, it will break down and be absorbed by the intestine faster than the solid food. It will line the intestine. Very soon, this will turn into fats and lead to cancer. It is best to drink hot soup or warm water after a meal.
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A serious note about heart attacks HEART ATTACK PROCEDURE': (THIS IS NOT A JOKE!) Women should know that not every heart attack symptom is going to be the left arm hurting. Be aware of intense pain in the jaw line. You may never have the first chest pain during the course of a heart attack. Nausea and intense sweating are also common symptoms. Sixty percent of people who have a heart attack while they are asleep do not wake up. Pain in the jaw can wake you from a sound sleep. Let's be careful and be aware. The more we know the better chance we could survive. 
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Source: Internet

International Success Story

Margie Wright, Australia's Star Diamond. Saved her entire DXN bonuses to purchase herself a car, which was her encouragement to reach Star Diamond, a great achievement at 78 years old. Her lovely new car replaces her very old and battered one. She is very proud and added a DXN number plate with her year of birth.

Source: Internet

Product Information – Glutathione in Cordyceps

Cordyceps Sinensis is considered one of the most valued Chinese medicinal herbs. It contains great amounts of important and active nutrients like: cordycepic acid, cordycepin, amino acid, Glutathione /glutamic acid, polysacharrides, vitamin B12 and more. There has been numerous research about Glutathione, one of the most valuable components of Cordyceps which is also a powerful naturally occurring antioxidant in all human cells.

Glutathione is found in all cells in the body, including the bile, the epithelial lining fl uid of the lungs, and also in the blood. The highest concentration of Glutathione is found in the liver, making it very important in the cleansing and elimination of free radicals. Accumulation of these dangerous free radicals can result in oxidative stress, which occurs when the generation of free radicals in the body
exceeds the body’s ability to neutralize and eliminate them. Metabolically, Glutathione has many functions. Glutathione plays a substantial role in the body’s immune system. Its antioxidant property makes it vital to white blood cells (lymphocytes) as it allows them to reach their full potential
during the oxygen-requiring activity of the body’s immune response.

Glutathione is known to have multiple functions. It detoxifi es many foreign compounds and abnormal cell producers, both organic and inorganic. It is essential for the immune system to exert its full potential and maintain control of the immune response. It plays a fundamental role in numerous metabolic and biochemical reactions such as DNA synthesis and repair, protein synthesis, prostaglandin synthesis, amino acid transport and enzyme activation. Thus, every system in the body can be aff ected by the state of the Glutathione system, especially the immune system, the nervous system, the gastrointestinal system and the lungs.

Glutathione is the regulator and regenerator of immune cells and it is the most valuable detoxifying agent in the body, detoxifi cation of toxins and carcinogens, enhancement of the immune system, and protection from oxidation and enzyme activations. Glutathione has strong antiviral properties. If there are higher levels of Glutathione in the tissues and serum, then the replication of most pathogens are stopped. Conversely, if the levels of Glutathione are low, then conditions become much
more favourable for viruses.

The health benefi ts of the Glutathione component in Cordyceps is extremely important to the immune system and to the general well-being.

Source: Internet

Eid Mubaruk

Eid Mubaruk to all

The Immune System. It’s what keeps us alive and kicking.

The Immune System.  It’s what keeps us alive and kicking.   Most of us don’t give much thought to our Immune System. We think it’s doing a pretty good job.  After all, the evidence is there.  When we get a cut, it heals. When we get a cold, we sneeze and cough, but it goes away.  When we have a stomach bug, we feel crook while our body fights off the cell invaders, but we spring back.

That’s all very well and good, but how do you know whether your immune system is truly functioning properly?  Is it sound enough to deal with more serious, long-term health risks and diseases?  Or are there areas that need improvement? Well, let’s go back to basics.  Just what is the Immune System and how does it work? To paraphrase Wikipedia:

“An Immune System is a system of biological structures and processes within an organism that protect against disease by identifying and killing pathogens and tumour cells.
The typical vertebrate Immune System consists of many types of proteins, cells, organs, and tissues that interact in an elaborate and dynamic network.  The human Immune System also adapts over time to recognize specific pathogens more efficiently. This adaptation process creates immunological memory.
Disorders in the Immune System can result in disease, including autoimmune diseases, inflammatory diseases and cancer.  Immunodeficiency diseases occur when the Immune System is less active than normal, resulting in recurring and life-threatening infections.  Autoimmune diseases result from a hyperactive Immune System attacking normal tissues as if they were foreign organisms.
Further investigation in the field of immunology is expected to play a serious role in promotion of health and treatment of diseases.”

Well, so now we should have a little more respect for the Immune System.
And we know it’ll work hard to keep us in good shape, but only if we reciprocate.
So that comes down to the air we breathe, the food we eat, the liquids we drink, and the workout we give it. In an ideal world we would consume healthy organic food, drink only pure water, breathe only fresh clean air, and stay active.  It’s really not rocket science!

But take a look around you!  Most of us live in crowded cities, leading busy lives, rushing to fit in all that needs to be done in a hectic day.  Fast food, short cut meals and sugary food and drinks tempt us constantly.  Who has time to source good ingredients to cook quality healthy meals?  Adults and kids alike are less active and as a consequence our society as a whole is getting fatter, and chronic preventable disease is on the rise.

So here our bodies are, working hard to compensate and keep up with the abuse we throw at them.  But this can’t go on forever without something giving way.  And imperceptibly, over the years, our bodies rebel.

There’s no shortage of early indicators of immune dysfunction.  You have been warned!
For example, recurrent viral infections, frequent colds and flu, inflammations and infection of the sinus, ears or throat and recurrent bronchitis or cystitis can be an obvious one.
Some people experience recurrent skin infections, like fungal problems (eg Candida), herpes, or bleeding gums.

Others find their energy levels are a problem, and just put it down to hard work or stress.  But poor stamina, sleepless nights, chronic fatigue and reduced resistance under stress may be your immune system wearing out.

And of course, there’s pain.  Gout, rheumatoid arthritis, acid reflux or heartburn and eczema are more than merely unpleasant experiences.  They’re a red flag that your immune system is undermined.
And when it comes down to the serious, potentially life threatening and debilitating conditions, like high blood pressure, high cholesterol and diabetes, you know your immune system is in real trouble.
So now you know why you should improve your immune system. But how can you? 
Our body is the best doctor.  We’ve already seen that we’re designed to fight disease with our natural immune systems. But we need to help it along a little.

People use excuses all the time to justify bad behaviour.  So just because you say, “I don’t have the time, energy or resources to lead a healthy lifestyle” doesn’t mean you can’t.
Supplementing your dietary intake with some of the super herbs like Ganoderma (otherwise known as Lingzhi or Red Reichi) and Spirulina is a great beginning.  That’s because when we really can’t get sufficient quality nutrients in our regular diet, (even when we try hard) it’s certainly much easier to turn to a high quality supplement.

These Immune System boosters, vitamins and supplements have been proven to be highly effective in improving and maintaining the Immune System.

Is it time for a cold hard look at your diet?
Naturally, your choice of food and cooking methods should be of prime importance, so let’s take a look at some immune boosting foods that should form the basis of your diet.
Time to go back to basics with raw fruits and vegetables (include raw vegie juices daily for a quick, easy shot), free-range eggs, oily fish, (salmon, sardines, tuna), avocados, fresh seafood, legumes, raw nuts and seeds.

• Spices such as chilli, ginger, raw garlic and onion. These also add interest to your cooking.
• Cold pressed seed and vegetable oils are certainly the standout oils.
• Raw fenugreek, fresh wheat-germ, flaxseed (cold pressed oil) barley grass, (juice or sprouted seeds) wheat grass juice, and freshly spouted seeds and beans.  Maybe a bit different to what you’re used to, but try some.
• Seaweeds such as kelp, dulse, agar-agar, nori, arame, kombu, wakame and hijiki are widely available in Japanese sushi and sashimi.
• Good old cruciferous vegetables like broccoli, cauliflower, cabbage, brussel sprouts and kohlrabi – don’t you just love them!  Many people don’t, but as they contain phyto-nutrients that protect against infections and cancer, it’s time to get more creative in your cooking and learn to love them!
• Foods such as soybeans, alfalfa and flaxseed contain good source of plant hormones, known to reduce the risk of many cancers.
• Minerals are vital for the Immune System.  Those especially beneficial are Magnesium, Zinc Chelate and Selenium.
• Ensure adequate vitamin C intake by eating citrus fruits, red onion and green peppers, kiwi fruit, tomatoes, and supplement if you need to, with approximately 1000 > 2000 mg per day Roselle Juice.
• Consume “Super Food” Supplements, like Ganoderma, Spirulina, Cacao, Maca, Aloe Vera, Hempseed, Goji Berries.
• Drink 8 to 10 glasses of filtered water daily even if you think you don’t need it.
• Make regular exercise a part of your daily regime. Exercise does wonders for your immune system and overall health, not to mention your looks!

So there you have it: a pocket guide to the Immune System.  It needs your help; and you can’t afford not to give it.  Is it time to get your house in order?

Spirulina - A short review on its Phytonutrients,Arginine, GLA and Phycocyanin

What is Arginine?Arginine is an amino acid (non essential) that has numerous functions in the body. It helps the body get rid of ammonia (a waste product), is used to make compounds in the body such creatine, L-glutamate, and L-proline, and can be converted to glucose and glycogen if needed. Arginine is used by the body to make the nitric oxide, a compound in the body that relaxes blood vessels. Preliminary studies have found that Arginine may help with conditions that improve when blood vessels are relaxed (called vasodilation), such as atherosclerosis and erectile dysfunction. Arginine also assists in keeping the blood clean. Arginine is important for the production of (male) seminal fluid which is about 80% arginine. DXN Spirulina contains 47.6 mg of Arginine. Ref: -Spirulina book from Harald W. Tietze. / Wikipedia

What is GLA – Gamma Linolenic acid ?The human brain is around 80% fat. Nerve tissues in the brain need “healthy” fats in order to function properly, and GLA is one of the healthiest fats you can consume. That’s why human breast milk contains high quantities of GLA. In fact, breast milk is the # 1 source of GLA on the planet, and Spirulina is #2. Breast milk contains GLA because infant humans need to quickly build brain mass in order to boost their chances of survival. Spirulina is highly recommended for the non breast-fed. Spirulina contains 35mg of GLA.

What is Phycocyanin ?Spirulina is Blue / Green algae. Green being Chlorophyll (stored sunlight) and blue being phycocyanin (helps produce new stem cells in the bone marrow). Blue pigmentation in foods is extremely rare. The chemical reality of Spirulina’s blue colour is demonstrated by its eff ect in the nervous system and brain. Here phycocyanin (a biliprotein) helps draw together amino acids for neurotransmitter formation, which increases mental capacity.

DXN Spirulina contains 420mg Phycocyanin. Recommended is 3 grams of Spirulina per day for maintenance and prevention.

Source, Natural News article by Mike Adams.

Best Health Boosting Medicinal Mushroom is Ganoderma (Reishi)

If you take only one medicinal mushroom, make it Ganoderma.  Also known as Red Reishi in Japan or Lingzhi  in China, Ganoderma Lucidum is a type of mushroom that’s renowned for its fantastic medicinal properties and has been used in traditional medicine throughout Asia for centuries.  Documents confirm it’s been in use for more than 2000 years. There are 2 parts to the mushroom, the red fruit body, and the root system.

Reishi Gano or RG capsules contain pure Ganoderma Lucidum powder from the fruit (that’s the red disc-like part in the picture). Ganocelium or GL capsules contain pure Ganoderma Mycelium powder from the root (they’re the long straggly bits).

RG contains over 400 different nutrients, while GL contains over 200.  So we’re talking about some very power-packed capsules.

And just why is this particular mushroom so good for you?
Talk to any practitioner of herbal, traditional and Chinese medicine, or any nutritionalist or naturopath.  In their rich armoury, medicinal mushrooms feature strongly.  There’s a reason for this.  Firstly, they’re a natural product (well, that stands to reason).
But mostly it’s because the nutrient-rich Ganoderma Lucidum medicinal mushroom is the most nutrient-rich of all the medicinal mushrooms.
Ganoderma contains a vast array of Polysaccharides, Organic Germanium, Adenosine, Tripterpines, amino acids, ganoderic acids, anti-oxidants, proteins, vitamins, minerals and enzymes. It’s also classed as an adaptogen, which means it can enter and clean toxic cells. Phew. That’s a lot for a single plant.  You can see why practitioners and users sing its praises.

The key benefits of Ganoderma reach all parts of the body More and more clinical research into Ganoderma is confirming what the practitioners of old already knew.  That Ganoderma can help reduce the incidence and effects of many major diseases and conditions. Here’s a snapshot of some of these studies.

1. Cardiovascular disease – in inhibiting platelet aggregation and reducing hypertension.
2. Immune system – in particular, in cancer research, recording positive immune-modulating effects and reduced side-effects from chemotherapy and radiation.
3. Blood sugar balance – with a blood sugar lowering effect, elevation of plasma insulin levels, and enhanced liver metabolism of glucose.
4. Anti-inflammatory effects – showing comparable effects to hydrocortisone.
5.  Liver protector - studies with Hepatitis B Patients found Ganoderma reduced the elevated levels of liver enzymes to normal range.
6. Oxygenation – a reduction in altitude sickness by oxygenating the blood.

And here’s good news especially if you have a busy lifestyle.
Ganoderma is the most alkaline food in the world.  You probably didn’t know this, but most of us have bodies that are in a state of acidosis.  Sadly, that’s not good news. In short, we eat too many acidic foods and drinks too many acidic drinks (even though they may not taste tart).

The body operates at its best and most efficient when in a slightly alkaline state.  But acidosis means that instead of being in a peak fighting state, it’s fighting with one hand tied behind its back.
Ganoderma helps restore the body’s pH balance to it’s preferred alkaline state.  With regular use, it’s back to a fair fight.  And with some 150 disease that can’t survive in an alkaline body, it’s a fight you really want to win.

You may feel fit and healthy now, but what happens when lifestyle catches up?
You’d be living under a rock not to know that chronic disease is on the rise.  And the seeds are sown early on.  It’s just that we don’t see it coming.

Diabetes, heart disease, arthritis, obesity and many other conditions are by and large a result of the body’s own immune system under stress.  The major organs that clean our cells become overloaded with a toxic mass because of lifestyle and eating choices and can’t cope.  This happens over a number of years.  It’s disease by stealth.

So the organs have to store those toxins in our cells until they can get around to dealing with them all.  Imagine it’s a bit like rubbish bins on the street.  Unemptied, the bins overflow, and turn nasty.  Before you know it, you’re dodging and weaving around mess.  And the smell!  Well, imagine your poor body having to storing up its waste in different parts of you and how inefficient that makes its functioning!
And once the cleaning functions are impaired, there’s only one way to go, and that’s downhill.
But a lot of this is reversible. Just because you have chronic disease, doesn’t necessarily mean you’re condemned to have it forever.  A change of attitude, diet and lifestyle, together with regular use of Ganoderma can and has been shown to reverse many conditions.

So now you know more about Ganoderma, do you think it could help you too?

Source: Internet

Monthly Meeting Schedule for September 2010

Parable of Pipeline - The Pattern of Success of DXN

Human body - The best doctor in the World (With Testimonials).

The doctor here referred to is the one on call inside our body. He works 24 hours a day to keep us healthy. When we catch a cold, he creates a river of mucus to carry the bacteria out of our body. When our cold settles in our chest and our lungs get congested, he makes us cough in order to rid our lungs of the congestion. When we get a fever, it is an indication that our own personal doctor is fighting off infection. If we eat something that does not agree with our body, our doctor induces vomiting to rid our body of the culprit. When our doctor senses abnormal cells, he immediately begins to encapsulate the suspected cells and form a tumor. A splinter is detected and in a few days, our doctor forces it out. While we are sleeping our doctor continues to work, cleansing our body and getting us ready to fight another day. If you want to keep your doctor in tip-top condition, give him plenty of water, fresh fruits, vegetables and proper nutrition and exercise. Remember your doctor is working harder than ever these days. While we want to keep him alert, we also want to give him the help that he needs to keep us healthy by leading an active life.

Courtesy - DXN News letter June 2004.

Help your doctor with DXN's RG & GL (100% Ganoderma) daily which he needs
If you are taking any other medicine under the advice of your medical practitioner, you should continue to use the same while taking this Reishi Ganoderma.

Reishi Ganoderma has got very good effect if combined with other line of treatments.
Become member of DXN and avail great discounts/bonus on your purchases and on the purchases of your down lines (conditions apply) , enjoy good health and get the blessings of persons relieved from the diseases.

If you search for 'Ganoderma" in internet using search engines, you will get more than 45,000 pages. This shows the awareness among peoples and research institutes, world wide.

Diseases cured by taking Reishi Ganoderma (as Claimed by the users)

The following testimonials are taken from DXN's News letters, Internet articles and DXN's organized meetings. I am not a doctor and the advice below does not replace professional medical treatment in any way. But it can be worth a good try. I am along with my family taking DXN's RG & GL (contains 100% Reishi Ganoderma) daily to maintain good health and found useful. Please note that Ganotherapy differs person to person depends up on their body composition and toxins deposited in the body.
Ganoderma does not have any side effects, however after using the product you might experience a reaction for a while. This is good sign and it means, the product is removing toxins from your body that are settled. After a few days, these reactions will diminish. For instance, if you suffer from Migraine headaches, your headache might even worse for a few days, but then it will disappear. If the reaction
gets too severe, cut your doses in to half for a few days.

Ganoderma does not cure any disease by itself, but it builds up your immune system
and restores the body functions. Your body, when in good shape is the best doctor
and can fight off any disease.

The interesting factor is that RG/GL pairs are used here for all the diseases/ailments. This RG/GL is taken for all the diseases since they contain 100% Reishi Ganoderma which works on cell level. When cell is corrected, the organ, composition of cells is corrected and hence whole body, composition of organs is
corrected. Some are using Ganozhi (tooth paste), Lingzhi Coffee, Cocozhi (health drink) as a support which also contain (15-28 %) Reishi Ganoderma.

The scientific data accumulated over the past 30 years help explain why Reishi Ganoderma is effective in all the parts of our body:

Our Body Systems and associated diseases



Abdominal Pain
1) Mr. Ch.P.B. Chowdary - (Irritable bowel syndrome, Manic depressive psychosis) - Suffering from 1980 - Obstinate constipation. Unbearable abdominal pain undergone gastroscopy, colonoscopy tests. Reports reveal that that there was inflamation of intestines and nothing could be traced out. I used to suffer unbearable pain i stomach and I was feeling at that time, it is better to die immediately instead
of living long with this great pain. With the advice of my good friend Mr.K. Papa Rao of Tanuku , I started taking RG & GL. 25.12.2002 to 31.03.2003 RG/GL 2 pairs thrice a day. Found relief from abdominal pain and constipation, psychiatric problem also relieved some extent. From 01.04.2003 onwards, I increased dosage RG 6, GL 10 daily. Besides, I am taking Morinzhi tonic twice a day, 2 in 1 coffee twice a day. DXN Tea twice a day (black tea with 2 drops of lemon juice). Both abdominal and psychiatric ailments are relieved by 90%, I am still continuing the above dosage.

Adenomyosis

1) Mrs. Priya Krishnan, 30 years - referred by Dr. Malathi Ramani - Known case of adenomyosis suffering from Nov 2000 was under various treatments - Scan - bulky uterus measuring 10.7 x 4.9 x 6.3 cm normal ovaries suggestive of adenomyosis, ginguvitis. On and off multiple ulcers in mouth. RG/GL 2 pairs morning and evening for 2 months suggested and Ganozhi paste for local application. History of painful periods and heavy bleeding, same dosage - 2 months under observation April -May. 14.05.2001, RG/GL 2 pairs 3 times a day for 2 months. Good improvement, no severe pain, no clots, gums improve. 19.06.2001, RG/GL 4 pairs for 3 months, Lingzhi coffee 3 times. Patient improved very well.

Asthma

1) Mr. Girish KUmar (19 years) - Suffering from asthma from 5 years onwards. Advised by the doctor Decadron tablets rgularly. Because of the side effects of the tablets, his body weight has increased abnormally, was not in a position to walk freely because of his body weight. Started gano with 3 pairs. Within 3 months, body weight became normal, asthmatic symptoms got cured and having a good quality of life. Taking all kinds of food without any diet restrictions. Remarks : My sincere thanks to
Mr.T.Rajendran and Mr.R.Senthilkumar for introducing to this miraculous product. My sincere thanks to Dr.Lim, Founder.

2) Mr.Ashwin - Asthmatic problem by birth. For the past 5 years taking inhalers continusously, weakness due to side effects of modern medicines. Started gano on 01.09.2003 with 2 pairs daily. Jan 2004 took the following dosage. 1st week - 2 pairs, 2nd-4 pairs, 3rd-5 pairs, 4th-6 pairs. Now maintaining with 1 pair a day. Today, I am fit and healthy. Inhalers stopped and no more suffering from asthma. Doing
Engineering.

3) Wong Meng Sam - Malaysia - I started following the DXN Dieting Therapy and took RG/GL Mix Powder on 16 June 2001. Every morning, I mixed the RGGL Mix Powder with 500 ml of water and shook the solution 100 times. Then I drank it when it was still full of oxygen. At noon, I ate as usual but kept the meal light and simple. At night, I prepared the RGGL Mix Powder solution again as in the morning and drank it. I also ate some fruits such as pineapple, pear, apple, guava or watermelon. In addition, I
maintained the habit of doing physical exercise everyday. After just 21 days, I lost 13.5kg in body weight. In addition, I no longer have any problems with hypertension, asthma and rheumatism that I was suffering from previously. Thanks to DXN for bringing to us such good products.

4) Mr. Oomer - India - Chronic Asthma : Regular use of inhaler Neutraliser + Oxygen tent in the evening in addition to oral tablets. 28.04.00 Given up oxygen tent. Using only neutraliser when necessary (SOS). Stopped tablets. Patient had piles problem and this also became all right. General feeling of well being felt by patient.

Back ache
1) HENRI PIPPER, Thousand Oaks, California - Disease : Lower backache, canker sores, bursitis,enlarged prostates. I live partly in Indonesia and because of my age I contracted a lot of these "Old Age Diseases". One day a lady in Indonesia came to me and asked me if I wanted to become a distributor for the DXN company. Having some experience with the MLM business in the US, I declined the offer, however just to do her a favor, I bought a small set of the RG and GL capsules. I took a pair of the
capsules every morning as soon as I woke up, just to see if it would do "anything" to me. I was a skeptic when it came to herbs, because when I was in the US, for about a year I went every week to an acupuncture clinic for my back pain and also with it took a lot of herbal remedies. Sometimes the pain disappeared for a while, however it always came back. My doctor told me that the only thing to operate on my back. (with some risk involved). After taking the pills for about two weeks I noticed that
I could sleep better, because my back pain didn't wake me up anymore. It was still there, however much less severe. My first thought was: oh, just a coincidence, but from that time on the pain became less and less. For the last twenty years or so I always had canker sores in the worst way. The pain was so bad, that sometimes I couldn't eat for several days. These canker sores were part of my life; any
remedy I took for it was strictly temporary. I am using the Ganoderma now for about eight months and since day one, I never had these sores again. I must confess however, that sometimes during the first four months, I got some blisters in my mouth, but by applying the RG powder (from the RG capsule) on the blister, it usually disappeared within two days, but without any significant pain. For the last three
months I never got any of these blisters again, no matter what I eat. I used to get it immediately after eating or drinking citrus products or by eating pineapple. Before taking the Ganoderma, I used to go to the bathroom about five times a night to urinate. Now, I go only before I go to bed and in the morning as soon as I get up. This is also a result of using this product I didn't even mention the other problems I
had: a bad knee, some arthritis in my elbow and right hand and stamina. Today I feel like a completely different person, I feel like I am 20 years younger and now I can do things again that I was unable to do before. MY CONDITION TODAY: No more canker sores, no bursitis, no knee pain, no more arthritis pain, smaller prostates. I still have a very slight back pain (about 5%), but only in the morning, however to a
point where I can live with it. I THANK GOD THAT I RUN INTO THIS PRODUCT.

Cancer

1) Mrs. Nalini - Small lump -1 biopsy taken at CMC Vellore - was diagnosed as breast cancer (right multiple lymph nodes + axillary + surgical procedure with chemotherapy was given. Patient's general condition became very weak, lost all hair with nutritional deficiency. Advised Ganotherapy and started from Sep 2000 1 pair to start with than increased gradually RG-2, GL-4 (6-6-6) for 2 months with regular follow up. December 2000, patient's general condition improved. RG-4, GL-8 (12-12-12) for 2
months with Gano coffee thrice. General health improved, weight gained, skin improved and good hair growth. CT scan chest and upper abdomen liver, gall bladder, spleen pancreas reveals no abnormality. No evidence of any enlarged nodes seen in the lower abdomen portahepatis and in relation to retro peripheral vessels. When compared with previous scan 04.09.2000, there is very minimal increase in the number of lesions. No evidence of any enlarged nodes in axilla. Patient clinically free from metastasis. Advised to be on RG-2, GL-4 (6-6-6) for 3 months, Gano coffee 3 times with regular follow up.

2) Mrs. Rajini Sarma, Karnrup, Assam. - She was suffering from Cancer of Oesophagus (Middle third)since last 1999 and was treated with Radio therapy in Dr.B. Barooah Cancer Institute, Guwahati, Assam and 8 months later again. She felt difficulty in swallowing both solid as well as liquid and recurrance of the same was seen. After necessary examination, she was advised to continue for a course of Chemo-therapy again and discharged with regular medical advice. But gradually her weakness
increased to ten fold, and wide spread metastasis was noticed in association with paralysis of both the lower limbs and a big bed sore on thelowe back. Patient does not want to take food and drink and crying all the time (day & night), tendency to take food is almost decreased except a few sips of water or liquid in some moments. As the day progressed, her general condition worsened and developed a kind of suicidal tendency scatting, "please give a poisonous injection so that I can die without anytrouble to the family" or "hit me with a bullet".. etc. Ganotherapy was started on 28th of January 2001with 2 pairs of RG + GL twice daily (consuming the capsule with milk/water) and noticed keenly. After two days, she could recover her hunger, felt very relaxed and sleepy on 6th day she asked for semi-solid food (masked rice with dal) and 9th day she asked to put oil on her hairs and wanted to sit in
early sun-light. Gradually her bed-sore reduced in size and feeling much better than earlier.

3) Mrs. Puttayamma, 60 years, referred by Dr.Malathy Ramani. 5th May 2000, cancer cervic, HB treated with radiotherapy. Biopsy poorly differentiated squamous cells, cancerous wound in vulvovaginal region, severe pain and purulent discharge. 21.09.2000, 1 pair for 1st week and 2 pairs morning and evening till 31.10.2000 and 3 pairs for one month. Patient general condition improved very well, side effects of radiotherapy had come down. 27.11.2000 started RG 2x2x2 for 6 days, GL 4x4x4 for 6 days. Patient was looking healthy. Pain had come down. Scan revealed the Tumour Mass had come down and no further spread. 04.12.2000 RG-3, GL-6 daily. General condition improved very well. 10.01.2001 - RG-2, GL-2 till April 2001. 15.07.2001 - General condition good, no weight loss. 17.11.2002 Scan revealed uterus atrophic size reduced, no free fluid. General condition good, 2 pairs daily for maintenance.

4) Shanthi - Suffering from Cancer, left breast since 2001 May. Had undergone the operation chemotherapy and radiation within 7 months. During the periodic check up at Adayar, they found that there is some growth in the right breast. Both fine needle aspiration test and the biopsy showed some calcification. I came to know about Ganotheraphy in March 2003 and started taking it regularly. I took RG 2+GL 4 twice daily with Morinzhi syrup. I believe that the RG and GL and Morinzhi has made
everything normal and above all God'shelp. Presently I am healthy and I am now working as nurse and social worker, working among the women groups> I visit my villag regularly and I feel I am alright.

5) Mrs. Rajini- India - Cancer : Monocytic Leukemia Terminal Case : WBC TC: 800: Hb: 5.1g. Presenting symptom : Bleeding gums, bleeding rectum, bleeding pervagina, Respiratory Distress, Every 5th day required blood transfusion. (Patient advised by cancer inst. to undergo bone marrow transplantation costing around Rs. 11 lakh failing which they can't assure her life beyond 5 days) 22.02.00 General Condition improved : WBC TC: 1200, Bleeding gums, PR & PV stopped completely.
29.02.00 WBC TC: 2400, Blood transfusion given Hb: 9.7g. 07.03.00 Hb: 9.1g, WBC TC: 2200 clinically stable. 15.03.00 General condition further improved, patient able to do all her work independently including outside work. 23.03.00 Additional protein mix given. Patient felt energetic and could handle her SIL's FIL's dealt with work load as a normal person. Hb: 8.7g WBC TC: 3300 23.04.00 Same condition, therapeutic plateau 09.05.00 Hb reduced, blood transfusion given after two months. Condition stable WBC : 1800

6) Mr. Ramalah - India - Cancer : Carcinoma both vocal cords. Treated with radiotherapy and chemotherapy. Patient all right for 3 months. On routine checkup, found out at cancer Inst. Recurrence of growth in left vocal cord. Advised immediate operation costing Rs. 30,000/- that the patient can not afford. 10.04.00 Condition Same 17.04.00 Condition improved with change of voice. Patient able to talk
clearly. 23.04.00 General well being felt by patient. Patient attended his work without problem. 01.05.00 After taking Lingzhi coffee along with RG-GL, patient developed increased appetite, gain weight and speed is normal. 25.05.00 Status Quo : Patient okay.

7) Mrs. Meng Yunqing - China - I was informed I had colon cancer in Dec. 2001. In Jan. 2002 I was operated on and started chemotherapy. In 2003, I was re-examined and operated on again, but only to find that the cancer had spread all over my belly. The doctor said that no therapy was needed and I left the hospital. I stayed in bed all day long and could not eat anything. My belly ached. Then, I took Ganoderma Lucidum. After I had taken one bottle, the ache decreased and my appetite increased. I
could even walk about in the room.

8) Mrs. Xie Yingyin - China - I was found bleeding, nasal obstruction, tinnitus in 2002. After examination, the report was that I got N-P.C., and started the chemotherapy in the Center Hospital. During the period, I had thirstily, sore-throat, WBC reduced & lost her appetite. When my husband got the news that Ganoderma Lucidum has a good function of anti-tumor, I started to take it. After taking it 10 days, the number of WBC increased obviously, while the side effects diminished. As a result of
these, the chemotherapy took over successfully. Now I can work normally.

9) Mrs. Qian'xiaochun - China - In July 1999, I got rectum cancer. After operation, I started three stages of chemotherapy every three month. But the side effects of the decrease of leukocyte were so sensitive that I became very weak. I had to stop chemotherapy. In Feb. 2002, one of my friend introduced Ganoderma Lucidum to me. After taking it, my body recovered, and my appetite improved. Since I took Ganoderma Lucidum, I have never had cold. My sleep improved. In June 2003, I was reexamined
thoroughly, and everything went well. I am a healthy person now.

Source- Internet

REISHI GANODERMA - GIFT OF GOD TO HUMAN BEINGS

Reishi Ganoderma classified as King of all herbs. It works in each cell of our body.
100% natural. No side effects has been reported even on prolonged use. It has a long history of safe use (more than 3000 years). Suitable for all as a food supplement.

Reishi Ganoderma works at cell level on the entire body. When cell is corrected, organs comprising of cells are corrected and thus our body comprising of organs is corrected. Reishi Ganoderma protects body from diseases as well as disorders. Gives health, vigor and vitality. Reduces stress, retards ageing process and increases life span. Effective for all age groups, from womb to tomb. Suits anybody and everybody. Has no interaction with other lines of treatment, It complements the same. Overcomes the side-effects of other medications and relieves the patients. No diet restriction. Liberal dosage schedule, mega dosage not harmful at all. No side effects, no addiction. Gano is for everybody, healthy as well as unhealthy. This single herb Gano gives recovery from the earlier ailments, maintenance of the present good health and protection from the future problems to health. Reishi is the Japanese name for Ganoderma Lucidum. The Chinese call it Lingzhi. Reishi contains 252 active elements. It contains Proteins, Amino acids, Vitamins, Minerals and dietary Fiber which are essential nutritional elements to build the body strong and healthy. Important 5 active elements which are available in Reishi for therapeutic benefits are as follows: (This 5 active elements in single herb makes Reishi Ganoderma a special herb.)

FAQ on DXN Ganoderma

1) What is all about?
This is all about a herb called Reishi Ganoderma also known as gift of God or King of herbs.

2) Why is it called King of herbs or Gift of God?
This is a special herb which contains more than 250 medicinal values. It works at our cell level and corrects each and every cell of our body. Our body comprises of cells will then be corrected and our all organs will function normally. When all organs do their job properly, we will not have any diseases/alments.

3) How do I belive this?
From Testimonials. Or search 'Reishi Ganoderma' with your favorite search engine. You will find more than 20,000 web pages. Where, you can find many articles on this special herb written by many Scientists, Universities and Research labs and Doctors.
Even though above all are true, as a human, we will believe only when we personally experience any thing. Take this herb with your food and experience it. You will believe it. Sure.

4) How safe is it to use? Any side effects?
It has been used by many people for the past 3500 years. So far, no adverse result is reported. There is no side effect even on prolonged usage. The herballous history of reishi had long been documented in the oldest Chinese pharmacopoeia written in about first or second century B.C. In that book, it had been recorded as having the most extensive and effective healing powers. The book, which are known in Japan as "Shinnoh Honoshkyo" is now accepted as being the original textbook of oriental medical
science. A number of countries are now conducting sophisticated research in reishi hoping to further the practice and science of medicine. Currently there are more than one million members all over the world who are satisfied users of the Reishi Ganoderma products, while at the same time, they are constantly improving their standards of life. These medicinal herb's world annual turn over is Rs. 20,000
crores. It shows its popularity. I take it regularly as a food supplement. But in some cases, while this herb removes toxins deposited in the body, some reactions can be noticed. But it will be only a temporary. For example, when diabeties patient takes this herb, it will first remove sugar deposited in the body. If any sugar test is taken at that time, the readings will be little bit high. But it will be temporary. On regular usage, sugar level will come to normalcy.

5) Is it existing for the past 3500 years? Why is it so popular only now?
It was very very rare and it was found one or two in 10,000 trees in the forest. It was very difficult to locate in earliy times. Chinese Kings used to send big envoys to locate this special herb. If found, it would be treated as a special occasion and they would celebrate it in a big manner. Chinese Kings believed that taking this Reishi Ganoderma would enhance their life time. Due to bio-technical development in recent times, Japanese Scientists succeeded in developing this Reishi Ganoderma..
They create artificial climate in hygienic condition suitable for Reishi Ganoderma to grow . Today, most advanced techniques such as cloning are applied to grow Reishi Ganoderma. Its capability to act on cell level and its effectiveness on Cancer cells made this so popular. Also technical advancement in recent times in communication is responsible for its popularity. Indian National Mushroom Research Centre is also succeeded in cultivating this herb in Nov. 2002. India will also join with China, Japan,Malaysia, France etc. in cultivating this Reishi Ganoderma soon..

6) Is it a drug?
No. Drugs Controller General India, New Delhi in his letter dated 03.05.2000, certified that Reishi Gano is a food supplement and not a drug. Government of India, Port Health Organisation issued a certificate of analysis for the purpose of customs clearance confirmed in its report No. F43/2000/540 dated 07.03.2000, that Mushroom Powder and Linzhi Coffee are fit for human consumption according to analysis report. An apple a day keeps the doctor away - this is old saying. New one is, Reishi
Ganoderma a day keeps you away from all diseases with long life and best of health as per WHO definition of health which is "complete well being of person physically, mentally, spiritually and socially.

7) I do not have any diseases. I am very healthy. Then why should I take this so
called special herb?
If the following statements are always true, then you need not take this herb.
a) I am sure that I take only nutrition food which takes care of my health and also increases my immune system.
b) There is no air pollution, water pollution in my area or where ever I go.
c) Neither me nor my ancestors affected by any diseases.
d) I am not using any chemical products.
e) I feel healthy and fresh, no tiredness or fatigue. I have good sleep and good hungry always. I have clean food habits.
f) I will not loose my temper at any cost
g) I am sure I will not have any diseases in future.
8) OK. Please give me direct answer for the above question.
I do not have any diseases. But, reasons for my taking this herb are:
1. Statements mentioned in (7) are not always true
2.We have to have good immune system to fight off any diseases.
3. Our daily food will not give us good immune system, we have to depend up on medicines to eradicate diseases when they attack.
4. These medicines most of the times, will have side effects.
5. Many diseases will not manifest immediately and will take time to come out, because they take time to grow..
6. Even though everybody will not get this hiding diseases, I don't know whether I will get it or not.
7. When diseases come out, we have to spend huge amount for treatment.
8. To avoid this huge expenses in future, I protect myself with small amount every month.
9) You said that personal experience is the only solution to believe this herb..
What is your personal experience? What made you to believe this herb?
When this herb was introduced to me, I did not believe. I thought that it would be like any other products. I do not have faith on the products which have much advertising. I came to know about this product from one of my friends when he had Diabetes. My father (aged around 80) was bed ridden due to high diabetes (400+), Numbness attacked my father's left leg. So he could not even stand for 2
minutes. My father is pensulin dependant and in spite of taking several medicines, the sugar level never reduced. This diabetes started worrying me. I started to think what would happen to me. wanted to reduce my father's sugar level and stop the numbness spreading all over the body. And also, I wanted to protect myself against attacking this dangerous diabeties.. Even though I decided to use, I
was little bit scared to use this unknown herb and so I started collecting information about this herb. I

visited so many web pages, attended so many seminars and lectures and then only I was convinced. I started Ganotherapy (taking Ganoderma is Ganotherapy) to myself first to test whether it is acceptable one or not. To my surprise, it was very very effective to me. I could find some difference in my body. Iwas able to realize that oxygen is taken to all over my body cells. Unbelievable freshness was attained. My weekly visitor headache was stopped then. My food in take was also increased. After using this herb for a month, I introduced it to my father. In 3 months, his sugar level was reduced to 140+ and his numbness is 80% reduced. Now he is taking this herb egularly. I experienced the effectiveness of this special herb and I understood the estimonials given by the users must be true,Now I do not scare about any diseases. I know, this herb will take care. Convinced?

10) Will this cure only Diabetes?
I think you have not fully read the testimonials. You must know one thing. This Reishi Ganoderma will not cure any diseases on its own. Confused? This is not meant for any particular disease. This will act on cell levels and make all organs to perform its functions normally. When all organs function normally, our body is ready to fight against any diseases. To know what are all the diseases were cured, click
here Whatever be the diseases, the healing method is common. It increases the immune system and make the immune system strong to fight against any diseases. Scientists are now in the process of finding a medicine for AIDS using this Reishi Ganoderma.

11) You have been talking about herb, herb. How it should be taken ? With food ?
This herb is available in various forms. Capsules (RG & GL contain 100% Reishi Ganoderma), Coffee (Lingzhi 80% world best coffee powder with 20% Reishi Ganoderma), Health drinks (Cocozhi 28% Reishi Ganoderma and Chocolate flavor) Ganozhi Toothpaste (multipurpose utility, people are using it as a face lotion, for itches, burns, stomach ache, head ache etc) Ganozhi soaps for skin. Gano message oil for body pains. Capsules can be taken with empty stomach for better results (persons having stomach
problems should take after food). To start with, one pair of RG & GL can be taken for a week and can be increased to two and if necessary for three. For healthy people one pair of RG & GL is enough and for unhealthy people, more than a pair of RG & GL is required. Lingzhi or Cocozhi can be taken many times a day. Apart from this RG & GL pair, Morinzhi essence can also be taken to have our nervous system strong.

12) You were talking about reactions. Can you elaborate it?
When taken this Reishi Ganoderma herb, the following process is undertaken in our body.
SCANNING : (1 to 30 days) During this process, the body cells are checked for Toxins and inacitivity. Most of these kinds of defects at the cell level are reported by way of REFLECTIONS through the external organs like eyes, nose, ear etc. This is just a diagnostic phase which normally within 6 weeks
of starting this Ganotherapy. This reflections can be seen for about 5 to 7 days.

DETOXIFICATION (CLEANSING) (1 to 30 weeks) During this phase, the unwanted/harmful matters (called the toxins are removed from the body. The body using its own natural excretory mechanism, which is activated by Ganoderma, carrying out this process. This phase takes place for about 5 to 12
days, depending on the level and quality of toxins. During this process of detoxification, water soluble toxins (eg. sugar, uric acid) find their exit through urine and sweat. Insoluble toxins (eg cholesterol)are easily disposed off through phlegm.
REGULATION (1 to 12 months) The bio-chemical as well as bio-electric factors of the body are balanced and the organ functions are regulated to normal levels.

BUILDING (6 to 24 months) In this phase, the damaged cells are repaired and reconstructed. Inactive cells are activated. Body's natural immune system is activated.

REJUVENATION (1 to 3 years) This is the ultimate aim of consuming this herb. It is a continuous process
through-out life and during the process, body gains youthfullness. Oxidation of the cells prevented and ageing of the cells delayed. The natural immune system is activated at cell levels.While taking this herb, it scans our body. If any problem is found, reaction will occur. Reactions will be a temporary one. If reactions occur, it means this herb is started working and starting to remove toxins deposited in our body. . Many people have hidden diseases which wait for appropriate time to manifest. During scanning, this herb will expose those hidden diseases/ailments by reactions. If a diabetic patient has blocks in his/her heart, some times it can not be detected unless there is a pain in the heart. There may be a chance for silent attack before detection. When taken this herb, if there is a block or blocks in the heart, he/she will get immediate pain in the heart because this herb tries to remove this block or blocks.. This enable the patient to take immediate ECG and appropriate treatment in the hospital to prevent heart attacks. When continuously this herb is taken, our heart
will become strong and we can prevent any heart attacks in the future. If a person who has stomach problems, he/she will get diarrhea for a while. It means all the toxins are getting removed through this.

13) What precautions should I take to use this herb? Any diet restrictions?
No precautions. No diet restrictions. But you should drink sufficient water.

14) Any age restrictions to use this herb?
No age restrictions. All human beings can take this.

15) Persons undergoing some other treatments should stop the treatment to use
this herb?
No. Never. They should not stop the treatments presently undergoing. They should take this herb along with the other medicines. This herb is more effective when taken along with other lines of treatments. Doctor who presently giving the treatment will reduce the dosage or stop the medicines for the ailments/diseases when this herb is continuously taken.

16) How long it will take to cure the diseases?
There is no time limit. Time taken for cure may vary person to person depending up on their body conditions, toxins deposit in the body etc. Normally it takes 30 days to scan the whole body. and 2 to 3 years for complete regeneration. This herb will work in our body very slowly. Slow and steady process and finally achieve the ultimate goal of good health.

17) Where I can get those products?
It is available in more than 30 countries. I need to know your location to give its address. Please email me to rubalkislu@gmail.com or dxnbangladesh@dxn2u.com

Source: Internet

Testimonials

Information by: Ms Malathy Raminy(DXN India)
more Testimonials coming soon......

Monthly Meeting Schedule For August-2010

GANODERMA LUCIDUM EXTRACT INHIBITS PROLIFERATION OF SW 480 HUMAN COLORECTAL CANCER CELLs

GANODERMA LUCIDUM EXTRACT INHIBITS PROLIFERATION
OF SW 480 HUMAN COLORECTAL CANCER CELLs

J.T. Xie 1,2, C.Z. Wang 1,2, S. Wicks 1,2, J.J. Yin 5, J. Kong 3, J. Li 3, Y.C. Li 3, C.S. Yuan 1,2,4,* 1Tang Center for Herbal Medicine Research, the Pritzker School of Medicine, University of Chicago, Chicago, USA

2Department of Anesthesia & Critical Care, the Pritzker School of Medicine,
University of Chicago, Chicago, USA

3Section of Gastroenterology, Department of Medicine, The Pritzker School of Medicine,
University of Chicago, Chicago, USA

4Committee on Clinical Pharmacology and Pharmacogenomics, the Pritzker School of Medicine,University of Chicago, Chicago, USA

5Center for Food Safety and Applied Nutrition, FDA, College Park, USA





Aim: Ganoderma lucidum is a commonly used Chinese herb and an important ingredient in traditional Chinese medicine herbal formulations for immune dysfunction related illnesses. The effects of this medicinal mushroom on human colorectal cancer cells have not yet been evaluated. In this study, we investigated the effects of Ganoderma lucidum extract using SW 480 human colorectal cancer cell line. Materials
and Methods: Two different fractions of Ganoderma lucidum extract, i.e., a fraction containing mainly polysaccharides (GLE-1), and a triterpenoid fraction without polysaccharides (GLE-2) were analyzed. Their antiproliferative activity was evaluated by cell proliferation assay and 3H-thymidine incorporation assay. Scavenging effects of DPPH radical were assessed using ESR-spectroscopy. Results: Our data showed that both GLE-1 and GLE-2 significantly inhibited the proliferation of SW 480 cells. The inhibitory effect of GLE-2 was much stronger than that of GLE-1. GLE-1 inhibited DNA synthesis in the cells and reduced the formation of DPPH radicals. Conclusion:
Ganoderma lucidum extract inhibits proliferation of human colorectal cancer cells and possesses antioxidant properties. Key Words: Ganoderma lucidum, colorectal cancer, SW 480, proliferation, reactive oxygen species, DPPH radicals.


Colorectal cancer is the second leading cause of cancer related death in the United States, and the second most prevalent cancer worldwide [1]. Half of the patients diagnosed with colorectal cancer eventually die from the disease; and only less than ten percent of patients with the metastatic cancer survive more than five years after diagnosis [1]. Although in its early stages the cancer can be cured by surgical resection alone, very often surgery is combined with adjuvant radio- and hemotherapy. Patients treated for advanced stage colorectal cancer with adjuvant chemotherapy show a 40% reduced risk of relapse [2]. Recently, controlled clinical trials support a multimodal, multidisciplinary approach to treating both early stage and advanced colorectal cancers [3, 4]. While advances continue to be made in developing effective treatment strategies for colorectal cancer patients,
chemotherapies are still limited by severe side effects and dose-limiting toxicity. The drug-related adverse events not only worsen patients’ quality of life,
but can also lead to their refusal to continue the potentially curative chemotherapy [5]. Patients with cancer often resort to complementary and alternative medical
means to treat the side effects of chemotherapy [6].

Ganoderma lucidum (or “Lingzhi” in Chinese) has long been recognized by Chinese medical professionals as a valuable herbal medicine in treating a number
of different illnesses [7]. Shizhen Li, a highly influential doctor in Chinese medicine from the Ming Dynasty (1368–1644 A.D.), recorded the effectiveness of Lingzhi
in his famous book, Ban Chao Gang Moo (“Comprehensive Pharmacopoeia”), and stated that taking Lingzhi over the long-term would build a strong, healthy body
and assure longevity. Ganoderma lucidum is often an important ingredient in traditional Chinese medicine herbal formulations for immune dysfunction related illnesses [7, 8]. Currently, there are several Ganoderma lucidum herbal products available. SunRecome is a commonly used Ganoderma lucidum product manufactured by
Shanghai Green Valley Pharmaceuticals in China. Previous studies showed that this herbal product could attenuate chemotherapy-induced nausea and vomiting in clinical trials [9] and animal studies [10]. Although human observational data in Chinese literature suggest that Ganoderma lucidum possesses an anticancer property [9], and the active anti tumor constituents are thought to be on the polysaccharides
[11], the effects of this medicinal mushroom on human colorectal cancer cells has not been evaluated. In the present study, we investigated the antiproliferative
effects of two fractions of SunRecome, i.e., a fraction containing mainly polysaccharides, and a triterpenoid fraction without polysaccharides, using SW 480 humancolorectal cancer cell line. Potential antioxidant activity of Ganoderma lucidum was also evaluated.


Received: December 22, 2005.
*Correspondence author: Fax: (773) 834-0601;
E-mail: cyuan@airway.uchicago.edu
Abbreviations used: DMSO — dimethyl sulfoxide; DPPH — 2,2‑Diphenyl-
1-picrylhydrazyl; ESR — electron spin resonance; GLE —
Ganoderma lucidum extract; ROS — reactive oxygen species.


Materials an d Methods Ganoderma lucidum extract (GLE) and test
solution preparation.

SunRecome, or Ganoderma lucidum extract (GLE), from one lot, was obtained from
Shanghai Green Valley Pharmaceuticals, China. The extract was analyzed by Shanghai Allsuccess Commodity Inspection Co., who reported that the extract contained 1.89% terpenoids and 15.8% polysaccharides using spectrophotometric methods. Fig. 1 shows
the chemical structure of terpenoids in Ganoderma lucidum. The extract was also analyzed by Applied Consumer Services (Hialeah Gardens, USA) to confirm that it was free of contamination such as microorganisms, pesticide residues, and toxic elements.



Fig. 1. General structure of terpenoids in Ganoderma lucidum Two different solutions were used to prepare GLE‑1
(a fraction containing mainly polysaccharides) and GLE-2
(a fraction containing triterpenoids without polysaccharides).
To prepare GLE-1, the extract powder was dissolved in 5% ethanol-water solution and placed in a 4 °C refrigerator over night. The following day the sealed
sample was heated in a water bath at 80 °C for 30 min. When the sample temperature cool down to room temperature, the solution was filtered with a Millex 0.2 μm
nylon membrane syringe filter (Millipore Co., Bedford, USA). To prepare GLE-2, the extract powder was dissolved in DMSO in room temperature, and then filtered
with a Millex 0.2 μm nylon syringe filter. To ensure that the cell growth was not affected by the DMSO, we studied the effect of DMSO alone on cell proliferation as a vehicle.

Cell Culture. Human colorectal SW480 cancer cell line (ATCC, Manassas, USA) was maintained in Leibovitz’s L-15 medium with 10% L-glutamine (Gibco, USA), supplementedsupplemented with 10% fetal bovine serum and penicillin-streptomycin (50 units/ml, Invitrogen, USA), in a humidified
incubator (5% CO2 in air at 37 °C) with medium change every 2–3 days. When the cells reach 70–80% confluency, they were trypsinized, harvested, and seeded into a new
tissue culture dish (100 mm in diameter).

Cell proliferation assay. On selected days after removal of incubation medium, SW480 cell monolayer was washed twice with phosphate buffered saline (PBS). To examine the antiproliferation effect of the extract, the cells were seeded in a 24-well plate at about 10,000 cells/well with regular medium and allowed to adhere for 24 h. After adhesion of the cells, the culture medium was changed prior to the addition of the test herbal extracts.
The cells were incubated with testing material at various concentrations for 72 h. Control cultures were incubated in culture medium alone. At the end of treatments, the
cells were detached using trypsin and counted using a Coulter Counter (Counlter Electronics, Hialeah, USA)[12, 13]. All assays were performed at least three times.
The inhibition of SW480 cell proliferation was calculated as follows: Cell proliferation (%) = 100 x (each cell number in experimental well/total cell number in the control well).


3H-thymidine incorporation assay. SW 480 cells were seeded in a 24-well plate and allowed to adhere for 24 h. The cells were incubated with GLE‑1 at various concentrations in 300 μl media containing 1 λ/ml 3H-thymidine (specific activity: 1.48 TBq /mmol 40.0 Ci/mmol) in each well for 72 h. Control cultures were incubated in the medium with 3H-thymidine only. After washing with PBS and 10% TCA (trichloroacetic acid), 0.5 ml NaOH (0.2 M) was added to each well and agitated for 5 min. Finally, the cell lysates were transferred into vials and 5 ml of 30% liquid scintillation was added and mixed in the vials. The radioactivity was measured using Liquid Scintillation Analyzer (Tri-Carb1500, Packard) [14].

Measurement of free radical scavenging ability of GLE-1 in a cell-free system. Antioxidant activity of Ganoderma lucidum was evaluated on the basis of its scavenging effect of DPPH radical using ESR pectroscopy [15]. Conventional ESR spectra were obtained with a Varian E-109 X-band spectrometer. ESR signals were recorded with 10 mW for DPPH, and 100 kHz field modulations of 2G. All measurements were performed at room temperature. The DPPH stable radical cavenging activity of GLE‑1 was estimated by ESR according to the method of Yamaguchi et al. [16]. The reaction mixture contained 50 μl test sample and 50 μl DPPH solution (0.5 mM). The proportion of ethanol/water in the reaction mixture was 5/95. ESR signaling was recorded at room temperature. Time dependence of the scavenging effect was determined by adding GLE-1 to the reaction mixture at 5 mg/ml for 2–15 min after mixing sample. Scavenging effect was determined by comparison with a control group. The dose dependency of the scavenging effect was also determined after GLE-1 addetion to the reaction mixture for 15 min. GLE-2 was diluted in DMSO. Since DMSO possesses antioxidant activity, we were unable to evaluate the free radical scavenging ability of GLE-2 in the cell-free system.

Statistical analysis. Data are expressed as mean ± standard error (S.E.). Statistical analysis was performed using ANOVA in combination with Student’s t-test. Differences were considered significant if P < 0.05. Results Inhibitory effect of GLE-1 on SW 480 cells. The inhibitory activity of GLE-1 on the proliferation of SW 480 human colorectal cancer cells at 72 h is shown in Fig. 2, a. GLE-1 decreased cell proliferation significantly in a concentration related manner. Compared to control
group (100%), GLE-1 reduced cell proliferation by 3.8 ± 4.5% at 0.05 mg/ml, 8.9 ± 5.2% at 0.25 mg/ml (P < 0.05), and 10.2 ± 5.0% at 1 mg/ml (P < 0.05).

Fig. 2. Antiproliferative effects of Ganoderma lucidum extract on SW 480 colorectal cancer cells after 72 h treatment. (a) Effects of GLE-1. (b) Effects of GLE-2. * P < 0.05; ** P < 0.01. Inhibitory effect of GLE-2 on SW 480 cells. The inhibitory activity of GLE-2 on the proliferation of SW 480 cells at 72 h is shown in Fig. 2, b. GLE-2 decreased the cell proliferation significantly in a concentration dependent manner. Compared to the control group, GLE-2 reduced cell proliferation by 18.1 ± 3.1% at 0.05 mg/ml (P < 0.05), 40.2 ± 3.7% at 0.25 mg/ml (P < 0.01), and 76.7 ± 1.8% at 1 mg/ml (P < 0.01).

Fig. 3. Time- and concentration-dependent inhibitory effects of Ganoderma lucidum extract on SW 480 colorectal cancer cells.
GLE-2 was used in this experiment. * P < 0.05; ** P < 0.01. Fig. 3 shows the time and concentration related
inhibitory effects of GLE-2 on the proliferation of SW 480 cells.



Fig. 4. Effects of Ganoderma lucidum extract on DNA synthesis. 3H-thymidine incorporation in SW 480 colorectal cancer cells was measured after 72 h of treatment. ** P < 0.01
Effects of GLE-1 on DNA synthesis by measuring
3H-thymidine incorporation. As shown in Fig. 4,c, treatment with GLE-1 for 72 h at 0.5 and 1 mg/ml suppressed cellular incorporation of 3H-thymidine significantly by 70.0 ± 0.6% and 73.0 ± 1.5% ompared with the control (both P < 0.01), respectively.
Free radical scavenging ability of GLE-1 in cellfree system. The radical scavenging activities of GLE-1 in a cell free system are shown in Fig. 5. Addition of GLE-1 to the DPPH system at a concentration of 5mg/ml remarkably reduced the free radical ESR signal after 2 min. After 15 min, the ESR signal of DPPH was totally eliminated. This time-related effect is shown in Fig. 5, a. The concentration-related scavenging effect of GLE-1 for 15 min is shown in Fig 5, b.



Fig. 5. Effects of Ganoderma lucidum extract on the ESR spectra of the DPPH radical in ethanol/water (20/80) solution. ESR time
points (b) spectra of the DPPH radical with GLE-1 are shown for different, and at different concentrations (a)

Discussion
Ganoderma lucidum is a commonly used herbal medicine in many Oriental countries. The anticancer effects of polysaccharides extracted from another species of genus Ganoderma were initially reported in 1971 [17]. Recently, some researchers observed
that triterpenoids in Ganoderma lucidum also are active antitumor constituents [18, 19]. In this study, two different solutions were used in the preparation of GLE-1 and GLE-2. Although both of the extracts showed inhibitory effects on the proliferation
of SW 480 human colorectal cancer cells, the percentage of inhibition was different, with much stronger inhibition using GLE-2. GLE-1 was prepared with 5% ethanol-water solution, which presumably dissolved mostly polysaccharides and a small percentage of terpenoids, while GLE-2 was prepared with DMSO, which presumably dissolved mostly terpenoids without any polysaccharides [11]. Thus, it seems that terpenoids in the GLE exert significant antiproliferative effects on the colorectal cancer cells in our experiments. In order to explore the possible mechanisms of Ganoderma lucidum’s anticancer activity, we evaluated the effect of the extract on the incorporation of 3H-thymidine in SW480 cells by using 3H-thymidine labeling assay. Our data suggest that the extract directly inhibits the synthesis of DNA in the cells [14]. Many herbal medicines possess antioxidant properties [20]. Antioxidants are compounds that protect cells against the damaging effects of reactive oxygen species (ROS). Some ROS, such as superoxide and hydrogen peroxide, are normally produced in cells as
by-products of biochemical reactions or as signaling molecules. When ROS-generating reactions are activated excessively, pathological quantities of ROS are released to create an imbalance between antioxidants and ROS, resulting in cellular damage. Oxidative stress was linked with the pathogenesis of many human diseases including cancer, aging, and atherosclerosis [21]. Herbal antioxidants may protect against
these diseases by contributing to the total antioxidant defense system of the human body [20, 22]. We observed e antioxidant effect of Ganoderma lucidum extract in our ESR study. The relationship between the observed antioxidant activity and the antiproliferation effect of SW 480 cells remain to be elucidated. In future
investigations, we will also use a panel of cell lines to provide us with the opportunity to evaluate whether the effects of a medicinal herb can be generalized across the spectrum of human cancers. In addition to its possible anticancer effect, Ganoderma lucidum may also help in decrease chemotherapy- induced side effects. We have demonstrated that the extract of Ganoderma lucidum attenuated cisplatin-induced nausea and vomiting in a rat model [10]. Cancer patients are known to use herbal products more often than the general population, and thus, well-investigated herbal therapies can offer patients with a practical alternative [6]. Moreover, if synergistic effects between herbal medicines and chemotherapy agents can be identified, reduction of chemotherapy dose in combination with herbs can further decrease dose-related drug toxicity. The identification of nontoxic anticancer herbal medicines remains an essential step in advancing the treatment of cancer. Data obtained from our studies has the potential to advance treatment regimens, and improve the quality of life of patients suffering from colorectal cancer.


References
1. Jemal A, Tiwari RC, Murray T, Ghafoor A, Samuels A,Ward E, Feuer EJ, Thun MJ. Cancer statistics, 2004. CACancer J Clin 2004; 54: 8–29.
2. Moertel CG, Fleming TR, Macdonald JS, Haller DG,
Laurie JA, Tangen CM, Ungerleider JS, Emerson WA, Tormey DC, Glick JH, Veeder MH, Mailliard JA. Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: a final report. Ann Intern Med
1995; 122: 321–6.
3. Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T,
Hainsworth J, Heim W, Berlin J, Baron A, Griffing S, Holmgren E, Ferrara N, Fyfe G, Rogers B, Ross R, Kabbinavar F. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350: 2335–42.
4. Moehler M, Teufel A, Galle PR. New chemotherapeutic
strategies in colorectal cancer. Recent Results Cancer Res 2005; 165: 250–9.
5. Schnell FM. Chemotherapy-induced nausea and vomiting:
the importance of acute antiemetic control. Oncologist 2003; 8: 187–98.
6. Ott MJ. Complementary and alternative therapies in
cancer symptom management. Cancer Pract 2002; 10: 162–6.
7. Bensky D, Gamble A, Stoger E. Chinese Herbal Medicine: Materia Medica. Eastland Press, Seattle, 2004.
8. Hijikata Y, Yasuhara A, Sahashi Y. Effect of an herbal
formula containing Ganoderma lucidum on reduction of herpes zoster pain: a pilot clinical trial. Am J Chin Med 2005; 33: 517–23.
9. Cheng J, Ren W. Anti-cancer research of SunRecome
and its clinical application: a review. Chin J Med 2003; 3: 689–93.
10. Wang CZ, Basila D, Aung HH, Mehendale SR,
Chang WT, McEntee E, Guan X, Yuan CS. Effects of Ganoderma lucidum extract on chemotherapy-induced nausea and vomiting in a rat model. Am J Chin Med 2005; 33: 807–15.
11. Gao Y, Tang W, Dai X, Gao H, Chen G, Ye J, Chan E, Koh HL, Li X, Zhou S. Effects of water-soluble Ganoderma lucidum polysaccharides on the immune functions of patients
with advanced lung cancer. J Med Food 2005; 8: 159–68.
12. Chang JS, Chiang LC, Hsu FF, Lin CC. Chemoprevention against hepatocellular carcinoma of Cornus officinalis in vitro. Am J Chin Med 2004; 32: 717–25.
13. Garmanchouk LV, Pyaskovskaya ON, Yanish YV, Shlyakhovenko VA, Dasyukevich OI, Solyanik GI. Influence of aconitine-containing herbal extract BC1 on proliferative and
electrokinetic characteristics of endothelial cells. Exp Oncol 2005; 27: 262–6.
14. Gieni RS, Li Y, HayGlass KT. Comparison of [3H]thymidine incorporation with MTT- and MTS-based bioassays for human and murine IL-2 and IL-4 analysis. Tetrazolium assays provide markedly enhanced sensitivity. J Immunol Meth 1995; 187: 85–93.
15. Kumar SS, Devasagayam TP, Bhushan B, Verma NC.
Scavenging of reactive oxygen species by chlorophyllin: an ESR study. Free Radic Res 2001; 35: 563–74. Experimental Oncology 28, 25–29, 2006 (March) 29
16. Yamaguchi F, Ariga T, Yoshimura Y, Nakazawa H. Antioxidative
and anti-glycation activity of garcinol from Garcinia indica fruit rind. J Agric Food Chem 2000; 48: 80–185.
17. Sasaki T, Arai Y, Ikekawa T, Chihara G, Fukuoka F. Antitumor
polysaccharides from some Polyporaceae, Ganoderma applanatum and Phellinus linteus. Chem Pharm Bull 1971; 19: 821–6.
18. Sliva D. Ganoderma lucidum (Reishi) in cancer treatment.
Integr Cancer Ther 2003; 2: 358–64.
19. Li CH, Chen PY, Chang UM, Kan LS, Fang WH,
Tsai KS, Lin SB. Ganoderic acid X, a lanostanoid triterpene, inhibits topoisomerases and induces apoptosis of cancer cells. Life Sci 2005; 77: 252–65.
20. Cadenas E, Packer L. Handbook of Antioxidants.
Marcel Dekker, Inc., New York, 2002.
21. Sauer H, Wartenberg M, Hescheler J. Reactive oxygen
species as intracellular messengers during cell growth and differentiation.
Cell Physiol Biochem 2001; 11: 173–86.
22. Chang WT, Dao J, Shao ZH. Hawthorn: potential roles
in cardiovascular disease. Am J Chin Med 2005; 33: 1–10.

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